Quantum computing represents a revolutionary computational paradigm with the potential to address challenges beyond classical computers’ capabilities. The development of robust quantum software is indispensable to unlock the full potential of quantum computing. Like classical software, quantum software is expected to be complex and extensive, needing the establishment of a specialized field known as Quantum Software Engineering. Recognizing the regional focus on Latin America within this special issue, we have boarded on an in-depth inquiry encompassing a systematic mapping study of existing literature and a comprehensive survey of experts in the field. This rigorous research effort aims to illuminate the current landscape of Quantum Software Engineering initiatives undertaken by universities, research institutes, and companies across Latin America. This exhaustive study aims to provide information on the progress, challenges, and opportunities in Quantum Software Engineering in the Latin American context. By promoting a more in-depth understanding of cutting-edge developments in this burgeoning field, our research aims to serve as a potential stimulus to initiate pioneering initiatives and encourage collaborative efforts among Latin American researchers.