Large Language Models (LLMs) perform well on basic programming problems. However, they encounter challenges when dealing with complex tasks, particularly programming competition-level problems. Notably, ChatGPT exhibits proficient performance on problems it has encountered during its pre-training phase, but this performance deteriorates when faced with novel problems. Consequently, enhancing the ability of LLMs to address unfamiliar problems has emerged as a pivotal research focus. The problem-solving process of LLMs mirrors human programmers’ approach to a certain extent. When confronted with new programming tasks, human programmers engage in task planning and code writing with the previously acquired knowledge about algorithms and data structures. Despite having learned such knowledge, LLMs struggle to effectively apply it when faced with specific new problems. To address this issue, we constructed a novel dataset, CodeF, which contains a portion of programming problems that ChatGPT has not previously encountered. Furthermore, we developed a Knowledge Library tailored for Python programming contest problems and introduced the concept of Knowledge-Aware Code Generation (KareCoder). KareCoder bolsters the models’ understanding and problem-solving capabilities by integrating prompt and knowledge from the library into the LLMs’ code generation reasoning process, especially on pass@1 metrics. Upon testing on the CodeF and APPS datasets, KareCoder demonstrated outstanding performance in handling novel problems previously unencountered by LLMs. In contrast with the code directly generated by ChatGPT, KareCoder achieved a relative improvement of 23.2% on the Pass@1 metric on the CodeF post2021-9 dataset. Additionally, it performs well compared to other methods when dealing with problems that LLMs have previously encountered. Our dataset and experiment data are open-sourced and can be accessed at https://github.com/CodeGeneration3/KareCoder.