Modern web applications are complex and used for tasks of primary importance, so their quality must be guaranteed at the highest levels. For this reason, testing techniques (e.g., end-to-end) are required to validate the overall behavior of web applications. One of the most popular tools for testing web applications is Selenium WebDriver. Selenium WebDriver automates the browser to mimic real user actions on the web. While Selenium has made testing easier for many teams worldwide, it still has its share of challenges. To better understand the challenges and the corresponding solutions adopted we decided to undertake a personal opinion survey from the industry (in total with 78 highly skilled participants), analyzing the most relevant challenges in end-to-end testing, with a focus on the Selenium ecosystem. The results allow understanding which challenges are considered more relevant by professionals in their daily practice and which are the techniques, approaches, and tools they adopt to face them. Therefore, this study is useful to (1) practitioners interested in understanding how to solve the problems they face every day and (2) researchers interested in proposing innovative solutions to problems having a solid industrial impact.