Using a hybrid approach to model central carbon metabolism across the cell cycle
Metabolism and cell cycle are two central processes in the life of a eukaryote cell. If they have been extensively studied in their own right, their interconnection remains relatively poorly understood. In this paper, we propose to use a differential model of the central carbon metabolism. After verifying it reproduces major known variations across the cell cycle’s phases, we extend it into a hybrid system reproducing an imposed succession of the phases. This first hybrid approach recovers interesting dynamical results, providing a good first step towards a more complex hybrid system.
Sat 6 Apr
|11:00 - 11:30|
|11:30 - 12:00|
|12:00 - 12:30|