ETAPS 2019 (series) / HSB 2019 (series) / 6th Workshop on Hybrid Systems & Biology /
Using a hybrid approach to model central carbon metabolism across the cell cycle
Metabolism and cell cycle are two central processes in the life of a eukaryote cell. If they have been extensively studied in their own right, their interconnection remains relatively poorly understood. In this paper, we propose to use a differential model of the central carbon metabolism. After verifying it reproduces major known variations across the cell cycle’s phases, we extend it into a hybrid system reproducing an imposed succession of the phases. This first hybrid approach recovers interesting dynamical results, providing a good first step towards a more complex hybrid system.
Sat 6 AprDisplayed time zone: Amsterdam, Berlin, Bern, Rome, Stockholm, Vienna change
Sat 6 Apr
Displayed time zone: Amsterdam, Berlin, Bern, Rome, Stockholm, Vienna change
11:00 - 12:30 | |||
11:00 30mTalk | A Hybrid HMM Approach for the Dynamics of DNA Methylation HSB Charalampos Kyriakopoulos Saarland University, Pascal Giehr Saarland University, Alexander Lück Saarland University, Jörn Walter Saarland University, Verena Wolf Saarland University | ||
11:30 30mTalk | Controlling noisy expression through auto regulation of burst frequency and protein stability HSB | ||
12:00 30mTalk | Using a hybrid approach to model central carbon metabolism across the cell cycle HSB Cecile Moulin Laboratoire de Recherche en Informatique, Université Paris-Saclay & UMR CNRS 8623, Laurent Tournier MaIAGE, INRA, Université Paris-Saclay., Sabine Peres Laboratoire de Recherche en Informatique, Université Paris-Saclay & UMR CNRS 8623. |