Digital solutions based on information and communication technologies (ICT) provide many opportunities in buildings to achieve resource and energy efficiency. In general, these solutions enable either monitoring or advanced control of buildings. The ICT solutions’ overall impacts on the environment are often presumed positive without a holistic approach based on life cycle thinking. The research on energy and indoor monitoring systems usually focuses on system performance and potential benefits rather than the entire system and it thus misses the life cycle impacts of the system itself. To address this limitation, the aims of this study are to assess life cycle environmental and resource impacts of a building monitoring system (BMS) and to identify hotspots in this system. The case study of KTH Living Lab represents an extensive BMS. It was applied and assessed using Life Cycle Assessment (LCA) methodology. The results show that wires, sensors and data acquisition equipment constitute hotspots for all the environmental and resource impacts assessed in this study. Thus, the impacts of these devices are important to consider by, e.g. building managers.