The task of content-type detection—which entails identifying the data encoded in an arbitrary byte sequence—is critical for operating systems, development, reverse engineering environments, and a variety of security applications. In this paper, we introduce Magika, a novel AI-powered content-type detection tool. Under the hood, Magika employs a deep learning model that can execute on a single CPU with just 1MB of memory to store the model’s weights. We show that Magika achieves an average F1 score of 99% across over a hundred content types and a test set of more than 1M files, outperforming all existing content-type detection tools today. In order to foster adoption and improvements, we open source Magika under an Apache 2 license on GitHub and make our model and training pipeline publicly available. Our tool has already seen adoption by a major email provider for attachment scanning, and it has been integrated with VirusTotal to aid malware analysis.