Responsible AI principles provide ethical guidelines for developing AI systems, yet their practical implementation in software engineering lacks thorough investigation. Therefore, this study explores the practices and challenges faced by software practitioners in aligning with these principles. Through semi-structured interviews with 25 practitioners, we investigated their methods, concerns, and strategies for addressing Responsible AI in software development. Our findings reveal that while practitioners frequently address fairness, inclusiveness, and reliability, principles such as transparency and accountability receive comparatively less attention in their practices. This scenario highlights gaps in current strategies and the need for more comprehensive frameworks to fully operationalize Responsible AI principles in software engineering.